Iowa State Cyclones Football Odds & 2025 Futures

Latest Cyclones Football Odds & Futures

The Cyclones’ odds to make the playoffs sit at +350, but if they continue to rack up wins, their playoff chances could improve even more as the season unfolds.

Win National Championship:	+12000 (0.8% chance)
Make College Football Playoff:	+350 (22.2% chance)
Win Big 12 Championship:	+650 (13.3% chance)
Odds Last Verified:	October 2025

Odds above are available at bet365 Sportsbook Iowa. All odds can vary across sportsbooks and are likely to shift as the season progresses.

2025 Iowa State Football Schedule & Betting Odds

The Cyclones’ schedule leans toward the more difficult side. Their rivalry game with Iowa is made even tougher following a trip to Ireland and a matchup against South Dakota, but wins in both games leave optimism for the road ahead.

Week	Opponent	Odds/Result
Week 0	@ Kansas State (Ireland)	W (24-21)
Week 1	vs. South Dakota	W (55-7)
Week 2	vs. Iowa	W (16-13)
Week 3	@ Arkansas State	W (24-16)
Week 4	BYE	N/A
Week 5	vs. Arizona	-5.5, ML -225
Week 6	@ Cincinnati	N/A
Week 7	@ Colorado	TBD
Week 8	BYE	N/A
Week 9	vs. BYU	TBD
Week 10	vs. Arizona State	TBD
Week 11	@ TCU	TBD
Week 12	BYE	N/A
Week 13	vs. Kansas	TBD
Week 14	@ Oklahoma State	TBD
Bowl Game	TBD	TBD
Odds Updated	October 2025

Odds last updated September 22, 2025 via DraftKings IA sportsbook. Throughout the 2025 college football season, these odds and results will be updated weekly.

Bet $5+ Get $200 in Bonus Bets If Your Bet Wins!

GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). Fees may apply in IL. 1 per new customer. Must register new account to receive reward Token. Must select Token BEFORE placing min. $5 bet to receive $200 in Bonus Bets if your bet wins. Min. -500 odds req. Token and Bonus Bets are single-use and non-withdrawable. Token expires 10/19/25. Bonus Bets expire in 7 days (168 hours). Stake removed from payout. Terms: sportsbook.draftkings.com/promos. Ends 10/12/25 at 11:59 PM ET. Sponsored by DK.

Where to Bet on Cyclones Football in 2025

You can claim any sportsbook promos in Iowa and start betting on Iowa State Football odds (specifically the Iowa at Iowa State game!). Here are a few of our favorites here at IowaBets.com:

Bet $50 Get $250 FanCash

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY: wager $10+ cash on any market with odds of -500 or longer to be eligible to receive $50 in FanCash each day for your first five (5) days. Terms, including FanCash terms apply - see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA)

Bet $5, Get $300 in Bonus Bets If Your Bet Wins!

Must be 21+ to participate. T&Cs apply.

Iowa State Cyclones Football Odds FAQs

The Iowa State Cyclones play football at Jack Trice Stadium, located on their campus in Ames, Iowa. With a seating capacity of over 61,000, it’s one of the premier venues in the Big 12 and a tough place for opponents to play.

Yes, you can legally bet on any Cyclones game in Iowa as long as you’re 21 and within state lines. To place bets, you’ll need to verify your age and location, which may include providing your Social Security number and allowing your mobile device to geolocate you before setting parlays on Saturdays.

Author

Tyler Olson

Tyler Olson has lived most of his life in Iowa, working in sports media for over a decade, writing and editing primarily NFL, sports betting, and iGaming content. His primary focus is giving sports bettors the most up-to-date information on legal operators, sharing the latest promo code offerings and analyzing team and player odds bettors can place bets on.